When was Wilma born?
When did Ws split from the N haplogroup?
Only research published in the last year, based on extensive tests of Asian populations, has provided a more complete answer to this question. The first migration of modern humans out of Africa began 60,000 to 80,000 years ago. Among these were ancestors of the the M and N haplogroups, descended from the African L3. These first Eurasian descendents of genetic Eve are believed to have expanded quickly along the Indian Ocean coastline (in this period there was dry land across what are now the mouths of the Red Sea and Persian Gulf). After a quick initial expansion along the coast, all the way to Australia, there was a slower conquest of the interior of Asia. Wilma, the first member of the W haplogroup, was born between 49,000 and 26,800 years ago in what is now northwest India or northern Pakistan. In the same area and in the same time periods women of the U7 and R2 haplogroups were born as well.
By between 40,700 and 23,300 years ago, these people were distributed in a band across southwest Asia, from Anatolia to northern India (the salmon-colored swath on the map). By a third route, through the valleys of Kashmir, a small group of W people reached central Asia between 36,000 and 19,100 years ago.
With the onset of the last glacial maximum, the area became extremely arid and the mountains blocked by glaciers. There are indications that the W-U7-R2 people were broken into two groups, separated by an arid desert that stretched from the Indian Ocean up to the glacier-bound Asian mountains. These tribes managed to survive in two areas of 'glacial refuge' (the red zones on the map). A similar refuge has been proposed in Spain for the ancestors of the H and V haplogroups that dominate in Western Europe.
After the glaciers receded and the deserts retreated 14,000 years ago, the way was clear for the expansion of modern humans from their ice age prisons. Wilma's descendants entered Europe through the Balkans, spreading in several directions. One lineage with a distinctive mutation at letter 119 in HVR2 settled in what is now France. Descendants of a woman with a change at letter 16362 of HVR1 spread from Central through Northern Europe and then to the British Isles. Lineages with very little change from their Wilman ancestor settled in sparsely-populated Finland and Scandinavia. But everywhere in Europe there were also other W lineages that shared ancestors with cousins still living in India, Pakistan, and Iran.

Echo of the past - average number of mutations from basic W haplotype in HVR1. A larger number indicates greater time depth.
Eurasia at the height of the last Ice Age (adapted from An Atlas of the Ice Age Earth).
Addendum: Definitions and Comments on W in the Scientific Literature
- W descended from N2. R2, U7, W form a cluster, suggesting intriguing links between West and South Asian mtDNA pools. Their spread and coalescence times suggest pre-Last Glacial Maximum gene flows in the area spanning from western India and Pakistan up to the Near East. As judged from coalescence time of the region-specific subclades, this genetic continuum was apparently interrupted by the expanding deserts in eastern West Asia during the Last Glacial Maximum (Metspalu, Mait: "Through the Course of Prehistory in India: Tracing the mtDNA Trail", PhD dissertation, Tartu, 2004.
- W descended from N*: 8994 16292. N descended from L3: 10873. W under 2% in Europe but 11% in Finns. Thought to originate 18,000 to 38,000 years ago (Roostalu, Urmas: "Towards the understanding of the origin of human genetic variation in Eurasian: mtDNA haplogroup H in the Caucasus", MSc Thesis, Tartu, 2004)
- W descended from common ancestor of N1b and I. W differs from this common ancestor by 709 5046 5460 7864 8994 11947 12414 12574 16292 195 225 227. W is defined by HVS1 motif 223 292 in an Iberian population. The cluster groups minor haplogroups W, I and N1b, the three are present although in low frequencies in Europe, Near East and Caucasus but only I and N1b have been also detected in Egypt and Arabia. (Nicole Maca-Meyer, Ana M González, José M Larruga, Carlos Flores and Vicente M Cabrera: "Major genomic mitochondrial lineages delineate early human expansions", BMC Genetics 2001, 2:13)
- Macrohaplogroup N in southwestern and Central Asia is partitioned into several branches: N1 (which also encompasses haplogroup I), N9a, A, W, X, and R. W diagnosed from N by 8994 and 16292. The proportion of western Eurasian lineages (HV, pre- HV, N1, J-T, U-K, I, W, and X) showed the opposite pattern of that exhibited by eastern Eurasian lineages. They exhibit their highest frequencies in the Anatolian/Caucasus and Iranian regions and their prevalence decreases eastwards. Despite this decreasing frequency cline towards the East, they are still present at relatively high frequencies in the Indus Valley and Central Asia. Indeed, the western Eurasian presence in the Kalash population reaches a frequency of 100%, the most prevalent haplogroups being U4, (pre-HV)1, U2e, and J2. (Quintana-Murci,Raphaelle Chaix, R. Spencer Wells, Doron M. Behar, Hamid Sayar, Rosaria Scozzari, Chiara Rengo, Nadia Al-Zahery, Ornella Semino, A. Silvana Santachiara-Benerecetti, Alfredo Coppa, Qasim Ayub, Aisha Mohyuddin, Chris Tyler-Smith, S. Qasim Mehdi, Antonio Torroni, and Ken McElreavey: "Where West Meets East: The Complex mtDNA Landscape of the Southwest and Central Asian Corridor" Am. J. Hum. Genet. 74:000-000, 2004).
- The significance ...for comparisons of the distributions of ... haplogroups of tropical (L0-L3) to temperate (H, V, U, J, T, I, X, N1b, W) or arctic (A, C, D, G, X, Y, Z) zones were calculated.... W and N1B both a branch from N.
- The numerous branches of N are, however, generally segregated to either the eastern (e.g. A, B, Y, R9) or western (e.g. N1, N2 (comprising of W and its sister-clade), TJ, HV, U) Eurasian-specific pools. With the exception of the diverse set of largely Indian-specific R lineages, the most frequent mtDNA haplogroup in India that derives from the phylogenetic node N is haplogroup W. The frequency peak of haplogroup W is 5% in the northwestern states - Gujarat, Punjab and Kashmir. Elsewhere in India its frequency is very low (from 0 to 0.9%) W and the other form a significant spatial cline. Coalescence estimates and diversity values for mtDNA haplogroup W in India: 37,900 ± 11,100 / 0.883 ; Near and Middle East: 32,000 ± 8,700 / 0.934; Central Asia 27,400 ± 8,300 / 0.758. Although haplogroup W is not highly frequent in European populations, it is nevertheless quite common, reaching the highest frequencies among the central-northern Finns (9%). Yet, it is virtually absent from the Finno-Ugric speaking populations of the Volga basin. In Central Asia the frequency of haplogroup W stays below 2%.Most of the extant mtDNA boundaries in South and Southwest Asia were likely shaped during the initial settlement of Eurasia by anatomically modern humans. (Mait Metspalu1, Toomas Kivisild, Ene Metspalu1, Jüri Parik, Georgi Hudjashov, Katrin Kaldma, Piia Serk, Monika Karmin, Doron M Behar, M Thomas P Gilbert, Phillip Endicott , Sarabjit Mastana, Surinder S Papiha, Karl Skorecki, Antonio Torroni and Richard Villems: BMC Genetics 2004, 5:26).
- Haplogroup cluster WIX harbored an unresolved reticulation composed of 1719G=>A and 8251G=>A, which, however, specifically determined the individual haplogroups. Haplogroup W could be divided into two subclusters. Subcluster W1 was highly starlike and was determined by polymorphisms 5495T?C and 12669C?T. The subcluster formed a large "pincushion and needles" structure, in which 15 samples had an identical genotype and 7 diverged from this by one or two polymorphisms. Subcluster W2 was determined by the polymorphisms 4928T=>C and 9612G=>A and encompassed 35% of the samples in haplogroup W. Interestingly, the heteroplasmic mutations 7706G=>A in COX II and 14696A=>G in tRNAGlu were confidently identified in haplogroup W. Phylogenetic Network for European mtDNA
Saara Finnila, Mervi S. Lehtonen, and Kari Majamaa Am J Hum Genet. June 2001; 68(6): 1475-1484.
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